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課程名稱 |
合成有機化學
Synthetic Organic Chemistry |
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開課學期 |
100-2 |
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授課對象 |
工學院 材料科學與工程學系 |
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授課教師 |
趙基揚 |
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課號 |
MSE5027 |
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課程識別碼 |
527 U3100 |
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班次 |
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學分 |
3 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期一6,7,8(13:20~16:20) |
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上課地點 |
綜103 |
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備註 |
限本系所學生(含輔系、雙修生)
總人數上限：50人 |
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課程簡介影片 |
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核心能力關聯 |
本課程尚未建立核心能力關連 |
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課程大綱
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課程概述 |
課程教學目標：
介紹常見之有機化合物之結構、物理特性、應用、製備、反應與相關之反應機構以及實際操作時之技巧。使同學對有機合成及常見之有機化合物有一初步之認識，並做為將來高分子合成及表面化學之基礎課程。 |
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課程目標 |
課程教學目標：
介紹常見之有機化合物之結構、物理特性、應用、製備、反應與相關之反應機構以及實際操作時之技巧。使同學對有機合成及常見之有機化合物有一初步之認識，並做為將來高分子合成及表面化學之基礎課程。
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課程要求 |
Chapter.1 Introduction to synthetic organic chemistry
1. General thoughts and procedures for a organic synthesis reaction
2. Common reaction intermediate: carbocation, carbanion, free radical and carbene
Chapter.2 Nucleophilic substitution and elimination
1. Bimolecular nucleophilic substitution (SN2) reactions
2. Unimolecular nucleophilic substitution (SN1) reactions
3. Unimolecular elimination (E1) reactions
4. Bimolecular elimination (E2) reactions
5. Comparison and problem solving strategy
Chapter.3 Alcohol
1. General aspects of alcohols: physical properties, nomenclature, spectroscopy and preparation
2. Oxidation of alcohols
3. Alcohols as nucleophiles and electrophiles; tosylation reactions
4. Reduction of alcohols
5. Reactions of alcohols with halide containing compounds
6. Reactions of diols
7. Reactions of alkoxides
Chapter.4 Ether, epoxides and sulfides
1. General aspects of ethers: physical properties, nomenclature, spectroscopy
2. Synthesis of ethers
3. Reactions of ethers
4. Sulfides
5. Synthesis of epoxides
6. Reactions of epoxides: ring opening, resin formation
Chapter.5 Aromatic compounds
1. Structure, physical properties and molecular orbitals of benzene
2. Aromatic, anti-aromatic and non-aromatic compounds
3. Aromatic ions
4. Heterocyclic aromatic compounds, polynuclear aromatic hydrocarbons and fused rings
5. General aspect of benzene derivatives: physical properties, nomenclature, spectroscopy
Chapter.6 Reactions of aromatic compounds
1. Electrophilic aromatic substitution
2. The effect of substituents: activator/deactivator and position directors
Chapter.1 Introduction to synthetic organic chemistry
1. General thoughts and procedures for a organic synthesis reaction
2. Common reaction intermediate: carbocation, carbanion, free radical and carbene
Chapter.2 Nucleophilic substitution and elimination
1. Bimolecular nucleophilic substitution (SN2) reactions
2. Unimolecular nucleophilic substitution (SN1) reactions
3. Unimolecular elimination (E1) reactions |
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預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
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參考書目 |
教科書:
1. L. G. Wade, Jr.: “Organic Chemistry” 6th ed., Pearson, 2006
主要參考書:
2. B. S. Furniss, A. J. Hannaford, P. W. G. Smith, A. R. Tatchell: “Vogel’s textbook of practical organic chemistry” 5th ed., Longman Scientific and Technical, 1989
3. John McMurry: “Organic Chemistry”, Thomson Brooks/Cole, 2005
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評量方式
(僅供參考) |
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